Discussions

Synthetic DNA Library Construction

Synthetic DNA library refers to a collection of DNA fragments stored in host microorganisms by molecular cloning. Each fragment can be stored in a host organism separately. By rapidly and accurately replicating DNA in host organisms and producing detectable quantities, we can have quick access to many different sequences of interest with ease and efficiency. Synthetic DNA libraries enable us to achieve gene synthesis and cloning faster, more intelligent, and more reliable.

Posted by cdbiosynsis 12 months ago

Animal Models for Ophthalmological Rare Diseases

Ophthalmological rare diseases are mostly inherited blinding eye diseases that severely damage the structure and function of the eye and seriously affect the physical and mental health of patients and their offspring. Ophthalmic diseases designated as orphan conditions have heterogeneous causes, including inherited genetic defects (e.g., Leber's congenital claustrophobia (LCA) and Stargardt's disease), autoimmune syndromes, or neovascular damage.

Posted by cathyysmith 12 months ago

Animal Models for Skeletal Rare Diseases

Skeletal rare diseases are a group of disorders that affect the development and maintenance of bone and cartilage tissues, leading to bone fragility, deformities, and growth abnormalities. These diseases are uncommon, with an estimated prevalence ranging from 1 in 10,000 to 1 in 100,000 individuals, depending on the specific disease. Due to their rarity and complexity, developing effective therapies is challenging. Currently, animal models have been used extensively in research on skeletal rare diseases to understand the underlying mechanisms of these diseases and test potential therapeutic interventions.

Posted by cathyysmith 12 months ago